Functional gastrointestinal disorders


Umbrella term compromising several age-dependent disorders. The disorders have no underlying structural or biochemical abnormality, but rather accompany the normal development of a child or arise from maladaptive behaviour. Even though the disorders are in general not dangerous, they often lead to distress for the paediatric patients and their parents (Benninga et al, 2016, Zeevenhooven et al., 2017).

Rome IV defines functional gastrointestinal disorders (FGID) as “disorders of gut-brain interaction. It is a group of disorders classified by [gastrointestinal] symptoms related to any combination of the following: motility disturbance, visceral hypersensitivity, altered mucosal and immune function, altered gut microbiota, and altered central nervous system (CNS) processing.” (Drossman, 2016)

Rome IV identifies seven FGID for neonates and toddlers including paediatric irritable bowel syndrome, functional constipation, functional diarrhoea, infant regurgitation, infant colic (Drossman, 2016, Benninga et al, 2016).